METHOD FOR CELLULAR LABORATORY IMMUNITY OF LABORATORY ANIMALS Russian patent published in 2019 - IPC A61K31/721 A61P37/00 

Abstract RU 2709809 C1

FIELD: veterinary medicine.

SUBSTANCE: invention refers to veterinary immunology, experimental and clinical pharmacology, particularly to developing a method of improving cell immunity of an organism, and can be used in laboratory work on studying cellular immunity. What is presented is a method for increasing cellular immunity of laboratory mice. Method involves using a biologically active preparation, according to the invention, the preparation used is a biotinylated derivative of oxidized dextran, which is a conjugate obtained by reacting biotin hydrazide and oxidized dextran with molecular weight of 40–70 kD with formation of azomethine bond, with intramuscular introduction in dose of 5 ml/kg of live mouse weight.

EFFECT: disclosed method enables to study the effect of BOD on cellular immunity in laboratory mice.

1 cl, 5 tbl

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RU 2 709 809 C1

Authors

Koptev Vyacheslav Yurevich

Shkil Nikolaj Alekseevich

Onishchenko Irina Sergeevna

Leonova Marina Aleksandrovna

Balybina Natalya Yurevna

Troitskij Aleksandr Vasilevich

Syrat Milena Viktorovna

Dates

2019-12-23Published

2018-10-22Filed