TREATMENT OF RETINITIS PIGMENTOSA WITH N-ACETYLCYSTEINE AMIDE Russian patent published in 2020 - IPC A61K31/195 A61P27/02 

Abstract RU 2711913 C2

FIELD: medicine.

SUBSTANCE: present group of inventions refers to retinitis pigmentosa treatment. Method of treating retinitis pigmentosa in a mammal, comprising administering to a mammal a therapeutically effective amount of a dose of N-acetylcysteine amide (NACA) of 100, 150, 300, 333, 400, 500, 600, 700, 750, 800, 900, 1000, 2500, 5000, 7500 or 10,000 mg per dose. Method of treating retinitis pigmentosa, involving identification of a person in need of treating retinitis pigmentosa, at least one of scotopic or photopic electro-retinogram and administering to a human a therapeutically effective amount of a solid dosage form of N-acetylcysteine amide (NACA) sufficient for treating retinitis pigmentosa of 100, 150, 300, 333, 400, 500, 600, 700, 750, 800, 900, 1000, 2500, 5000, 7500 or 10,000 mg per dose.

EFFECT: above described methods are effective for treating retinitis pigmentosa, doses higher than 100 mg of NACA are well tolerated.

17 cl, 4 dwg

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RU 2 711 913 C2

Authors

Hartman, Daniel

Campochiaro, Peter, A

Dates

2020-01-24Published

2015-11-06Filed