FIELD: medicine.
SUBSTANCE: invention refers to medicine, namely to a method of preventing preeclampsia in pregnant women with a factor F2G20210A mutation. Method for preventing preeclampsia in pregnant women with a mutation of factor F2G20210A, consisting in using calcium nadroparin when determining a prothrombin activity index of 171.0 % and higher to 18 weeks gestation, and further administration of preventive doses of calcium nadroparin is determined individually taking into account prothrombin activity, determined in period of 18 weeks and 28 weeks of pregnancy.
EFFECT: method described above is simple to use and enables to reduce preeclampsia (PE) by 46,7 %: from 56,7 % to 10 %: RR: 0,1765; 95CI: 0,0725–0,4291; p=0,0001 and improve pregnancy outcomes.
1 cl, 2 dwg, 3 ex
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