METHOD FOR PREDICTING THE RISK OF DEVELOPING PREECLAMPSIA IN WOMEN BASED ON GENETIC MARKERS Russian patent published in 2023 - IPC G01N33/58 C12Q1/6806 C12Q1/6827 C12Q1/686 C12Q1/6876 C12Q1/6883 

Abstract RU 2795660 C1

FIELD: medicine; medical diagnostics.

SUBSTANCE: invention can be used to predict the risk of developing preeclampsia in women of Russian nationality. DNA from the peripheral venous blood is isolated. The analysis of polymorphic variants rs1799945 of the HFE gene and rs805303 of the BAG6 gene is carried out. When a combination of genotypes GG rs1799945 of the HFE gene and GG rs805303 of the BAG6 gene is detected, a high risk of developing preeclampsia is predicted.

EFFECT: method provides for obtaining new criteria for assessing the risk of developing preeclampsia in women of the Russian nationality based on data on interlocus interaction of polymorphic variants rs1799945 of the HFE gene and rs805303 of the BAG6 gene.

1 cl, 2 dwg, 6 ex

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RU 2 795 660 C1

Authors

Abramova Mariya Yurevna

Ponomarenko Irina Vasilevna

Churnosov Mikhail Ivanovich

Dates

2023-05-05Published

2022-08-16Filed