FIELD: medicine; medical diagnostics.
SUBSTANCE: invention can be used to predict the risk of developing preeclampsia in women of Russian nationality. DNA from the peripheral venous blood is isolated. The analysis of polymorphic variants rs1799945 of the HFE gene and rs805303 of the BAG6 gene is carried out. When a combination of genotypes GG rs1799945 of the HFE gene and GG rs805303 of the BAG6 gene is detected, a high risk of developing preeclampsia is predicted.
EFFECT: method provides for obtaining new criteria for assessing the risk of developing preeclampsia in women of the Russian nationality based on data on interlocus interaction of polymorphic variants rs1799945 of the HFE gene and rs805303 of the BAG6 gene.
1 cl, 2 dwg, 6 ex
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Authors
Dates
2023-05-05—Published
2022-08-16—Filed