METHOD OF PRODUCING A PEPTIDE WHICH MODULATES PURINERGIC RECEPTOR ACTIVITY Russian patent published in 2020 - IPC C07K14/00 C07K19/00 C12P21/02 

Abstract RU 2714114 C1

FIELD: biotechnology.

SUBSTANCE: invention relates to biotechnology, specifically to recombinant production of biologically active polypeptides, which have modulating action on involved in generation of pain signal cell receptors, and can be used to produce peptide PT6 in an expression system of E. coli.

EFFECT: invention provides high-efficiency production of peptide PT6, which modulates purinergic receptor activity, in Escherichia coli BL21 (DE3) cells with high output.

1 cl, 7 dwg

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RU 2 714 114 C1

Authors

Stepanenko Vasily Nikolaevich

Makarov Dmitry Aleksandrovich

Zinchenko Alexei Alexeevich

Oparin Petr Borisovich

Sokolova Irina Vladimirovna

Vorobyeva Tatiana Vladimirovna

Levandovskaya Kristina Georgievna

Pavlenko Daniil Mikhailovich

Nokel Elena Adamovna

Puchkov Ilya Alexandrovich

Gordeeva Elena Anatolievna

Miroshnikov Anatoliy Ivanovich

Myagkikh Igor Valentinovich

Vassilevski Alexander Alexandrovich

Dates

2020-02-11Published

2019-08-30Filed