AGENT POSSESSING CYTOTOXIC ACTIVITY Russian patent published in 2020 - IPC A61K31/192 C07C15/27 A61P35/00 A61P35/02 

Abstract RU 2714932 C1

FIELD: chemistry.

SUBSTANCE: invention relates to organic chemistry and pharmacy. Disclosed is application 2-(4-carboxybenzylidene)-3,4-dihydronaphthalen-1(2H)-one as an agent possessing cytotoxic activity. Invention can be promising in medical practice for treating cancer diseases and obtaining agents having cytotoxic action, which can be used as active components of antineoplastic drugs, including against leukemia.

EFFECT: compound suppressed metabolic activity of pig embryo kidney cell lines carrying oncovirus A and C (SPEV), rat glioma (C6), human cervix uteri cancer tumor (HeLa).

1 cl, 3 dwg, 1 tbl

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RU 2 714 932 C1

Authors

Ivanova Aleksandra Leonidovna

Fedotova Olga Vasilevna

Kanevskaia Irina Vladimirovna

Fomin Aleksandr Sergeevich

Shirokov Aleksandr Aleksandrovich

Dates

2020-02-21Published

2019-09-26Filed