FIELD: organic chemistry.
SUBSTANCE: invention relates to a method of producing 4,5-diarylazoles, the general formula of ‘
where X=O, NH; R1=-Ph(OCH3)3; R2=-PhOCH3, with the following representatives: 4-(3,4,5-trimethoxyphenyl)-5-(4-methoxyphenyl)oxazole (compound A-123124), and 4-3,4,5-trimethoxyphenyl) -5-(4-methoxyphenyl)pyrazole (compound A-123127), have high antiproliferative activity IC50<10-12–10-10 mol against human and mouse tumor cells of different histogenesis. The production method includes the following steps 
EFFECT: invention provides a high yield of target products, while the synthesis is carried out from available raw materials.
1 cl, 12 dwg, 5 ex
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