FIELD: medicine.
SUBSTANCE: invention relates to use of a derivative of general formula I
,
where R1 and R2 independently of each other represent hydrogen, n is integer between 1 and 2, R3 is a -OH group or -O(C1-C6 alkyl), R4 is C1-C6 alkyl group, R5 and R6 independently represent a halogen atom or a pharmaceutically acceptable salt thereof as a therapeutic agent for treating and/or preventing muscular atrophy in mammals, and/or to limit muscular atrophy in mammals, and/or to stimulate muscle growth in training mammals seeking to increase muscle mass and quality, preventing symptoms of sarcopenia related to age or rehabilitation after loss of muscles, age-related muscular atrophy and/or consequences of drug treatment, and/or immobilisation, and/or cachexia.
EFFECT: disclosed are derivatives used for treating muscular atrophy.
12 cl, 1 dwg, 3 tbl
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Authors
Dates
2020-03-02—Published
2016-04-14—Filed