NEW OXIME CHOLEST-4-EN-3-ONE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND METHOD FOR PREPARING Russian patent published in 2013 - IPC C07J41/00 C07J43/00 A61K31/58 A61K31/575 A61P25/28 

Abstract RU 2496784 C2

FIELD: medicine, pharmaceutics.

SUBSTANCE: invention refers to oxime cholest-4-en-3-one derivatives of formula (I) and pharmaceutically acceptable salts and optical isomers thereof, and using them as cytoprotective drugs, as well as a based pharmaceutical composition. The radical values in general formula are presented in the patent claim.

EFFECT: compounds may be used as a cytoprotective drugs, including neuroprotective, cardioprotective and/or hepatoprotective drugs, a drug for protecting kidney cells, muscle cells, for treating or preventing necrosis and/or pathological apoptosis and/or necroptosis, and as a marker or labelling agent.

34 cl, 2 ex

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RU 2 496 784 C2

Authors

Prjuss Rebekka

Nazikh Abdesslam

Shembo Korinn

Druo Sirill'

Dates

2013-10-27Published

2009-07-29Filed