FIELD: medicine, pharmaceutics.
SUBSTANCE: invention refers to oxime cholest-4-en-3-one derivatives of formula (I) and pharmaceutically acceptable salts and optical isomers thereof, and using them as cytoprotective drugs, as well as a based pharmaceutical composition. The radical values in general formula are presented in the patent claim.
EFFECT: compounds may be used as a cytoprotective drugs, including neuroprotective, cardioprotective and/or hepatoprotective drugs, a drug for protecting kidney cells, muscle cells, for treating or preventing necrosis and/or pathological apoptosis and/or necroptosis, and as a marker or labelling agent.
34 cl, 2 ex
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Authors
Dates
2013-10-27—Published
2009-07-29—Filed