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2 716 709

(13)

(51)

IPC

A61K31/192(2006-01-01)

A61K31/167(2006-01-01)

A61K47/02(2006-01-01)

A61K47/04(2006-01-01)

A61K47/12(2006-01-01)

A61K47/26(2006-01-01)

A61K47/38(2006-01-01)

A61K9/16(2006-01-01)

A61K9/48(2006-01-01)

A61P31/12(2006-01-01)

(21) (22)

Application

2019126363, 2019-08-20

(24)

Start date

2019-08-20

(22)

Actual filing date

2019-08-20

(45)

Published

2020-03-16

(72)

Inventor

Shishkina Larisa NikolaevnaSheremet Olga PetrovnaMadonov Pavel GennadevichKorchazhnikova Nataliya PetrovnaBormotov Nikolaj IvanovichSkarnovich Maksim OlegovichSelivanov Boris AlekseevichSergeev Aleksandr AleksandrovichTikhonov Aleksej YakovlevichKarunin Vladimir NikolaevichAgafonov Aleksandr PetrovichMaksyutov Rinat Amirovich

(73)

Holder

Federalnoe Byudzhetnoe Uchrezhdenie Nauki Nauchnyj Tsentr Virusologii I Biotekhnologii Federalnoj Sluzhby Po Nadzoru V Sfere Zashchity Prav Potrebitelej I Blagopoluchiya Cheloveka Gnts Vb Rospotrebnadzora)

ORAL DOSAGE FORM OF THE PREPARATION IN CAPSULES FOR TREATING AND PREVENTING ORTHOPOXVIRUS-RELATED DISEASES Russian patent published in 2020 - IPC A61K31/192 A61K31/167 A61K47/02 A61K47/04 A61K47/12 A61K47/26 A61K47/38 A61K9/16 A61K9/48 A61P31/12

Abstract RU 2716709 C1

FIELD: medicine; pharmaceutics.

SUBSTANCE: invention refers to an oral dosage form of a capsule formulation effective against VV (variola virus) and other human and animal pathogenic orthopoxviruses, and can be used in pharmaceutics, virology, medicine and veterinary science. Ready dosage form contains as an active compound having anti-orthopoxvirus activity 7-[N-(4-trifluoromethylbenzoyl)-hydrazinocarbonyl]-tricyclo[3.2.2.02,4]non-8-ene-6-carboxylic acid (NIOH-14), lactose monohydrate, amorphous silicon dioxide anhydrous (aerosil), magnesium stearate and microcrystalline cellulose (MCC), potato starch, sodium chloride and purified water in the amounts specified in the claim.

EFFECT: technical result of the invention consists in expanding the range of ready dosage forms used in medicine and veterinary science for treating and preventing orthopoxvirus-mediated diseases.

1 cl, 2 dwg, 4 tbl, 9 ex

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RU 2 716 709 C1

Authors

Shishkina Larisa Nikolaevna

Sheremet Olga Petrovna

Madonov Pavel Gennadevich

Korchazhnikova Nataliya Petrovna

Bormotov Nikolaj Ivanovich

Skarnovich Maksim Olegovich

Selivanov Boris Alekseevich

Sergeev Aleksandr Aleksandrovich

Tikhonov Aleksej Yakovlevich

Karunin Vladimir Nikolaevich

Agafonov Aleksandr Petrovich

Maksyutov Rinat Amirovich

Dates

2020-03-16—Published

2019-08-20—Filed