FIELD: pharmaceutics.
SUBSTANCE: invention refers to chemical-pharmaceutical industry. Fluorescent sensor for detecting lysosomes in vitro contains a BODIPY family fluorophore, wherein fluorophore contains 4,4-difluoro-5-phenyl-3-(1,5-diphenyl-3-1H-pyrazolyl)-8-trifluoromethyl-4-bora-3a, 4a-diaza-8-indacene.
EFFECT: invention provides a fluorescent sensor having high photostability, low toxicity, which enables reliable detection of lysosomes in living cells and suitable for lifelong staining.
1 cl, 5 dwg, 3 ex
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Authors
Dates
2020-03-20—Published
2019-06-25—Filed