FIELD: chemistry.
SUBSTANCE: invention relates to organic chemistry and specifically to a heterocyclic compound of the formula given below, where R1 is hydrogen or halogen; R2, R3, R4 are hydrogen or halogen, with the exception of benzyl 2-((2-(3,5-dimethyl-1H-pyrazol-1-yl)-4-oxoquinazoline-3(4H)-yl)oxy)acetate, capable of inducing ferroptosis in metastatic melanoma and colon cancer cells.
EFFECT: technical result is obtaining novel quinazoline derivatives having useful biological properties.
1 cl, 2 dwg
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Authors
Dates
2020-05-28—Published
2019-07-04—Filed