METHOD FOR EARLY PREDICTION OF CHRONICITY OF PAIN IN HERPES ZOSTER Russian patent published in 2020 - IPC A61B10/00 G01N33/573 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to neurology and clinical immunology, and can be used for early prediction of chronic pain chronic zoster. Additionally, immunological indices of metalloproteinase-2 (MMP-2), metalloproteinase-9 (MMP-9), tissue inhibitor of matrix metalloproteinases-1 (TIMP-1), ratio of matrix metalloproteinase-9 to tissue inhibitor of matrix metalloproteinase-1 (MMP-9) are determined/TIMP-1). If the serum level of MMP-2 is less than 115 ng/ml, MMP-9 is more than 351.5 ng/ml, the ratio MMP-9/TIMP-1 is more than 1.5, an unfavorable prognosis of a high risk of developing post-herpetic neuralgia is stated.

EFFECT: method enables evaluating the prognosis in the patients with herpes zoster, which enables early assessment of the risk of chronic neurosis pain syndrome and development of postherpetic neuralgia by complex examination by determining and analyzing the serum level of MMP-2, MMP-9, TIMP-1, MMP-9/TIMP-1.

1 cl, 2 ex