APPARATUS AND METHOD OF MEASURING VEGETATIVE FUNCTIONS FOR DIAGNOSING AND CONFIRMING THE CLINICAL EFFECTIVENESS OF THE PATIENT AND THE RESULTS THEREOF Russian patent published in 2020 - IPC A61B5/00 

FIELD: medicine.

SUBSTANCE: invention relates to bioanalytical analysis. What is presented is a system using the measurement of direct pain biosignals for diagnosing pain and assessing the effectiveness of the treatment results, comprising: apparatus for measuring activity of a pain matrix, comprising a set of sensors configured to be placed on the body contralateral, and at least one additional sensor, configured to be placed on the body ipsilateral, wherein said device is configured to measure differences in voltage or current, obtained from measurements of the contralateral sensor to determine the reaction of the pain matrix as a deviation of the corresponding biosignal, indicating an increase or decrease of the individual sensation of pain; wherein said device is configured to measure differences in impedance, conductivity, voltage or current based on measurements of one of contralateral transducers and at least one ipsilateral sensor for calibration and normalization of the biosignal obtained from contralateral sensors; constant machine-readable medium in network of central processors, having a memory and a data storage and having a computer program implemented thereon, causing one or more central processors to perform certain steps; controller and/or processor, configured to: collect and obtain data on activity of the pain matrix from signals of the contralateral and ipsilateral sensors; obtaining access to measured activity of pain matrix and data, associated with biophysical, biological, psychological, social, environmental and demographic information on the patient and other patients; identifying a population with similar data, associated with biophysical, biological, psychological, social, environmental and demographic information on the patient and other patients; determining treatment or results of treating a patient and a similar population and correlating said treatment and treatment results with biosignal deviations, associated with pain matrix activity to determine the clinical effectiveness of the patient.

EFFECT: invention provides higher efficiency of bioanalytical analysis.

36 cl, 47 dwg