FIELD: chemistry.
SUBSTANCE: invention relates to a method of producing monochloroacetates of substituted 5-, 6-, 7-aminoindoles, which involves reacting corresponding substituted 5-, 6-, 7-aminoindoles in benzene heated with boiling with monochloroacetic acid.
EFFECT: obtained novel salts, such as 2,3-dimethyl-1H-indole-5-ammonium monochloroacetate, 1,2,3-trimethyl-1H-indole-5-ammonium monochloroacetate, 2,3-dimethyl-5-methoxy-1H-indole-6-ammonium monochloroacetate, 5-methoxy-1,2,3-trimethyl-1H-indole-6-ammonium monochloroacetate, 2,3-dimethyl-1H-indole-7-ammonium monochloroacetate and 1,2,3-trimethyl-1H-indole-5-ammonium monochloroacetate, can be used as water-soluble synthetic antimicrobial preparations.
1 cl, 6 ex
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Authors
Dates
2020-06-25—Published
2019-08-09—Filed