NOVEL DISUBSTITUTED 1,2,4-TRIAZINE COMPOUND Russian patent published in 2020 - IPC A61K31/53 A61K31/5377 A61K31/541 A61K31/553 A61P1/16 A61P3/04 A61P9/00 A61P9/04 A61P9/08 A61P9/10 A61P9/12 A61P13/12 C07D253/65 C07D253/07 C07D401/04 C07D403/04 C07D403/14 C07D405/04 C07D405/14 C07D409/14 C07D413/04 C07D413/14 C07D417/04 C07D417/14 C07D471/04 C07D471/08 C07D498/08 C07D498/10 

Abstract RU 2726410 C2

FIELD: medicine.

SUBSTANCE: invention relates to a method of treating various diseases and/or pathological conditions caused by high aldosterone and/or excessive production of aldosterone, where diseases and/or pathological conditions represent heart failure, nephropathy and sleep apnoea syndrome, provided that hypertension is eliminated, which involves administering a therapeutically effective amount of a compound of formula [I], values of radicals in which are given in the claim.

.

EFFECT: technical result: a method of treating heart failure, nephropathy and sleep apnoea syndrome caused by high aldosterone and/or excessive production of aldosterone by novel compounds of formula [1].

11 cl, 44 tbl, 373 ex

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RU 2 726 410 C2

Authors

Ushirogochi, Hideki

Sasaki, Wataru

Onda, Yuichi

Sakakibara, Ryo

Akahoshi, Fumihiko

Dates

2020-07-14Published

2015-04-23Filed