FIELD: chemistry.
SUBSTANCE: invention relates to a compound with formula (I) 
, where Ar1 is an imidazolyl group, which can be substituted with 1-3 substitutes; Ar2 is a pyridinyl group, pyrimidinyl group or phenyl group, which can be substituted with 1-2 substitutes; X1 is (1) -C≡C- or (2) double bond etc., which can be substituted, R1 and R2 are, for example, C1-6-alkyl group or C3-8-cycloalkyl group, which can be substituted; or to a pharmacologically acceptable salt of the said compound and pharmaceutical drugs for lowering production of Aβ42, containing formula (I) compound as an active ingredient.
EFFECT: wider field of use of the compounds.
26 cl, 1119 ex, 31 tbl
| Title | Year | Author | Number |
|---|---|---|---|
| MORPHOLINE TYPE CINNAMIDE DERIVATIVE | 2006 |
|
RU2381225C1 |
| PIPERAZINE DERIVATIVES | 1994 |
|
RU2124511C1 |
| SPHINGOSINE-1-PHOSPHATE BINDING INHIBITOR | 2007 |
|
RU2395499C2 |
| DERIVATIVE OF CYCLIC AMINE, CONTAINING HETEROARYL CYCLE | 2004 |
|
RU2346935C2 |
| HETEROCYCLIC COMPOUND | 2006 |
|
RU2382781C2 |
| PYRIMIDYL INDOLINE COMPOUND | 2008 |
|
RU2464269C2 |
| DERIVATIVES OF PHENYLALKYLCARBOXYLIC ACID AND PHARMACEUTICAL COMPOSITION BASED ON THEREOF | 1997 |
|
RU2169141C2 |
| CONDENSED HETEROCYCLIC NITROGEN COMPOUNDS AND USING THEM AS INHIBITORS OF AMYLOID BETA PRODUCTION | 2010 |
|
RU2515976C2 |
| SUBSTITUTED PROPANAMIDE DERIVATIVE AND PHARMACEUTICAL COMPOSITION CONTAINING SUCH DERIVATIVE | 2006 |
|
RU2394560C2 |
| TRICYCLIC HETEROCYCLIC COMPOUNDS AND JAK INHIBITORS | 2012 |
|
RU2632870C2 |
