FIELD: medicine; oncology.
SUBSTANCE: group of inventions can be used for treating cancer. For this purpose, disclosed is a combination of compounds described by structural formulas II and IV, as well as use of compound II simultaneously or sequentially with compound IV, IV compounds simultaneously or sequentially with compound II, and compounds I simultaneously or sequentially with compounds II and IV.
EFFECT: group of inventions provides higher clinical effectiveness in cancer by synergetic effect of combined introduction of anticancer agents in a lower dose than when administered separately, with reduction of side effects thereof.
19 cl, 17 dwg, 20 tbl
Title | Year | Author | Number |
---|---|---|---|
COMPOSITION AND METHOD OF AUTOIMMUNE DISEASES TREATMENT | 2012 |
|
RU2621129C2 |
PHARMACEUTICAL COMPOSITIONS FOR TREATMENT OF HELICOBACTER PYLORI | 2014 |
|
RU2671400C2 |
COMPOUNDS, COMPOSITIONS AND METHODS SUITABLE FOR CHOLESTEROL MOBILISATION | 2011 |
|
RU2576402C2 |
COMPOUNDS FOR TREATING TRIPLE-NEGATIVE BREAST CANCER AND OVARIAN CANCER | 2019 |
|
RU2776897C2 |
SPHYNGOSINE KINASE INHIBITORS | 2006 |
|
RU2447060C2 |
COMBINATIONS CONTAINING TRANSDUCTION SIGNAL INHIBITOR AND EPOTILONE DERIVATIVE | 2002 |
|
RU2313345C2 |
SELECTIVE ANTAGONISTS OF EP4 RECEPTOR FOR CANCER TREATMENT | 2010 |
|
RU2563817C2 |
PHARMACEUTICAL COMBINATIONS CONTAINING PYRIDO[4,3-d]PYRIMIDINE DERIVATIVES AS HSP90 INHIBITOR AND HER2 INHIBITOR | 2009 |
|
RU2532375C2 |
DERIVATIVES OF N-PHENYL-2-PYRIMIDINEAMINE, METHOD OF THEIR SYNTHESIS, PHARMACEUTICAL COMPOSITION ON SAID AND METHOD OF INHIBITION (TREATMENT) OF TUMOR | 1994 |
|
RU2135491C1 |
2-CARBOXAMIDE CYCLOAMINO UREA DERIVATIVES IN COMBINATION WITH HSP90 INHIBITORS FOR TREATING PROLIFERATIVE DISEASES | 2012 |
|
RU2624493C2 |
Authors
Dates
2020-07-21—Published
2016-10-06—Filed