MULTISPECIFIC BINDING PROTEINS WITH MUTANT DOMAINS FAB Russian patent published in 2024 - IPC C07K16/28 C07K16/46 A61K39/395 A61P37/00 

Abstract RU 2827657 C2

FIELD: biotechnology.

SUBSTANCE: invention relates to a multispecific antigen-binding protein, as well as an antigen-binding protein. Compositions and host cells for expression of said proteins are also disclosed. Invention also relates to a pharmaceutical composition for treating a disorder in which antigen activity has a negative effect.

EFFECT: invention enables effective heterodimerisation of antigen-binding proteins.

25 cl, 12 dwg, 11 tbl, 7 ex

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RU 2 827 657 C2

Authors

Amaral, Marta

Beil, Christian

Focken, Ingo

Hessler, Gerhard

Hoelper, Soraya

Jung, Jennifer

Lange, Christian

Leuschner, Wulf-Dirk

Rao, Ercole

Tiwari, Garima

Weil, Sandra

Dates

2024-10-01Published

2019-12-23Filed