METHOD FOR DETERMINING AN ADVERSE PROXIMAL PROGNOSIS IN THE PATIENTS WITH PNEUMONIA IN INFLUENZA A/H1N1 BY THE NATURE OF SERUM FERMENTEMIA Russian patent published in 2020 - IPC A61B5/1455 G01N33/573 

FIELD: medicine.

SUBSTANCE: invention refers to medicine, namely to resuscitation, therapy, and can be used to determine an unfavorable immediate prognosis in the patients with pneumonia in A/H1N1 influenza by the nature of serum fermentemia. Patient with pneumonia in influenza A/H1N1 is diagnosed with an oxygenation index PaO2/FiO2 and an assessment of the clinical-laboratory criteria of sepsis in accordance with The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). Laboratory levels of AST, ALT, LDH and CPK enzymes in blood serum are assessed with subsequent evaluation of the nearest disease prediction by fermentemia level. If the oxygenation index is within range of 300 to 200 mm Hg inclusive and the patient has no signs of sepsis, the fermentemia level does not affect the nearest prediction. If the patient's oxygenation index is less than 200 mm Hg with no signs of sepsis, the unfavorable outcome in assessing the nearest prognosis develops when the fermentemia increases from the reference level: LDH in 2.48 times and more, CPK in 3.36 times and more, AST in 2.35 times and more. If the patient's oxygenation index is less than 200 mm Hg and signs of sepsis are detected, the unfavorable immediate prognosis develops at fermentemia level AST in 2.65 times and more, ALT 2.3 times and more from the reference level.

EFFECT: method provides determining the unfavorable proximal prognosis in the patients with pneumonia in A/H1N1 influenza by the nature of serum fermentemia by conducting a patient with pneumonia in influenza A/H1N1 determining an oxygenation index and assessing the clinical-laboratory criteria of sepsis in accordance with current recommendations and laboratory assessment of blood serum AST, AST, LDH and CPK level.

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