FIELD: aerosol generation for therapeutic purposes.
SUBSTANCE: application of the method of spraying a composition containing polyclonal immunoglobulin (Ig), where concentration of Ig is 40–200 mg/ml and where viscosity of composition, measured by means of a viscometer with a falling ball at temperature of 20±0.1 °C, is 1–17 mPa·s. Method comprises the steps of: (a) preparing a liquid aqueous composition comprising immunoglobulin (Ig); (b) providing a membrane nebuliser having a reservoir, which is filled with composition; and (c) spraying the composition using a nebuliser to produce an aerosol.
EFFECT: invention provides successful spraying of concentrated immunoglobulin compositions.
15 cl, 8 dwg, 19 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| METHODS AND COMPOSITIONS FOR PREVENTION OR TREATMENT OF ACUTE COMPLICATIONS USING POLYCLONAL IMMUNOGLOBULIN | 2019 |
|
RU2806443C2 |
| PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORINE | 2006 |
|
RU2421209C2 |
| COMPOSITIONS CONTAINING SECRETOR-LIKE IMMUNOGLOBULINS | 2013 |
|
RU2644240C2 |
| AQUEOUS COMPOSITIONS CONTAINING ARBEKACINE | 2012 |
|
RU2604767C2 |
| DELIVERY OF ALPHA-1 INHIBITOR OF PROTEINASE INTO LUNGS | 2007 |
|
RU2433841C2 |
| PHARMACEUTICAL PRODUCT WITH INCREASED STABILITY, CONTAINING IMMUNOGLOBULINS | 2015 |
|
RU2748841C2 |
| AQUEOUS AEROSOL PREPARATION | 2004 |
|
RU2363449C2 |
| INTRODUCTION OF ILOPROST IN FORM OF AEROSOL BOLUSES | 2012 |
|
RU2605849C2 |
| HUMAN IMMUNODEFICIENCY VIRUS REPRODUCTION INHIBITOR | 2009 |
|
RU2396278C1 |
| INHALER DEVICE FOR USE IN AEROSOL THERAPY OF RESPIRATORY DISEASES | 2015 |
|
RU2700650C2 |
