MULTICOMPONENT NANOSIZED SYSTEM FOR DIAGNOSIS AND THERAPY OF NEW GROWTHS Russian patent published in 2020 - IPC A61K49/06 A61P35/00 A61K47/02 A61K33/24 A61K33/26 A61K33/242 A61K33/32 A61K33/34 A61K33/38 B82Y5/00 B82Y30/00 

Abstract RU 2729617 C1

FIELD: medicine.

SUBSTANCE: invention can be applied in medicine. Multicomponent nanosized system for diagnosis and therapy of new growths consists of a nucleus formed from silicon dioxide, titanium dioxide, zirconium dioxide or their composites, inner layer containing copper oxide, manganese dioxide, double oxide of iron or their composites, outer layer containing metal nanoparticles of silver, gold or their bimetallic particles, and biologically active molecules – biomarkers.

EFFECT: invention enables to obtain a multicomponent nanosized system having a core-shell structure containing spherically aggregative stable monodispersed particles, as a contrast agent for magnetic resonance and computed tomography and as a base for drugs targeted delivery of drugs in anti-tumor therapy.

1 cl, 6 dwg, 3 ex

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RU 2 729 617 C1

Authors

Blinov Andrei Vladimirovich

Blinova Anastasiia Aleksandrovna

Gvozdenko Aleksei Alekseevich

Raffa Vladislav Viktorovich

Golik Aleksei Borisovich

Iasnaia Mariia Anatolevna

Shevchenko Irina Mikhailovna

Maglakelidze David Guramievich

Senkova Anna Olegovna

Dates

2020-08-11Published

2020-02-07Filed