USE OF THE COMPOUND OF FORMULA I, A PHARMACEUTICAL COMPOSITION, A MEDICINAL AGENT Russian patent published in 2020 - IPC A61K31/352 C07D311/60 A61P27/02 

Abstract RU 2730854 C2

FIELD: chemistry; pharmaceutics.

SUBSTANCE: invention relates to use of a compound of Formula I, where R1, R2, R3, R4 and R5 each independently denotes a group selected from hydrogen, hydroxyl, C1-6-alkoxy, provided that one of R1, R2, R3, R4 or R5 denotes hydroxyl; R6 denotes hydrogen; R7 denotes hydrogen; R8, R9, R10 and R11 each independently denote a group selected from hydrogen and hydroxyl, provided that one of R8, R9, R10 or R11 is hydroxyl; X- denotes an anion selected from: an anion derived from a mineral acid, such as, for example, an anion of bromide, chloride, borotetrafluoride or perchloride; for treating, preventing and/or stabilizing age-related macular dystrophy (AMD), Stargardt disease, pigmentary retinopathy and/or diabetic retinopathy. Invention also relates to new specific derivatives of flavylium chloride, a pharmaceutical composition and a medicinal agent based thereon.

EFFECT: compounds with photoprotective activity are observed, which is useful in treating certain eye diseases.

9 cl, 4 dwg, 7 tbl, 3 ex

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RU 2 730 854 C2

Authors

Fontaine, Valerie

Lafont, Rene

Sanel, Jose Alain

Veillet, Stanislas

Dates

2020-08-26Published

2016-05-27Filed