FIELD: chemistry; pharmaceutics.
SUBSTANCE: invention relates to use of a compound of Formula I, where R1, R2, R3, R4 and R5 each independently denotes a group selected from hydrogen, hydroxyl, C1-6-alkoxy, provided that one of R1, R2, R3, R4 or R5 denotes hydroxyl; R6 denotes hydrogen; R7 denotes hydrogen; R8, R9, R10 and R11 each independently denote a group selected from hydrogen and hydroxyl, provided that one of R8, R9, R10 or R11 is hydroxyl; X- denotes an anion selected from: an anion derived from a mineral acid, such as, for example, an anion of bromide, chloride, borotetrafluoride or perchloride; for treating, preventing and/or stabilizing age-related macular dystrophy (AMD), Stargardt disease, pigmentary retinopathy and/or diabetic retinopathy. Invention also relates to new specific derivatives of flavylium chloride, a pharmaceutical composition and a medicinal agent based thereon.
EFFECT: compounds with photoprotective activity are observed, which is useful in treating certain eye diseases.
9 cl, 4 dwg, 7 tbl, 3 ex
Authors
Dates
2020-08-26—Published
2016-05-27—Filed