METHOD FOR DIAGNOSING CHRONIC ENDOMETRITIS IN FEMALES WITH ENDOMETRIOSIS Russian patent published in 2020 - IPC G01N33/577 G01N1/30 

Abstract RU 2731413 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to pathological anatomy and gynecology, and aims at diagnosing chronic endometritis in females with endometriosis. Endometrium pipelle-biopsy is performed in middle stage of proliferation phase or menstrual cycle secretion phase. Obtained biomaterial is immunohistochemically studied by staining the slits using a monoclonal antibody – Bond Ready-to-Use Primary Antibody CD68. Amount of CD68 macrophages is determined by counting the number of positive-colored cells by 1 mm2. If the number of positive-stained CD68 cells of endometrium is 1 mm2 at the middle stage of proliferation from 151 to 293 or in the middle stage of the secretion phase from 425 to 523, chronic endometritis is diagnosed. If the number of positive-stained CD68 cells of endometrium is 1 mm2 at the middle stage of the proliferation phase from 49 to 150 or in the middle stage of the secretion phase from 74 to 424, this corresponds to the norm.

EFFECT: invention provides effective diagnosis of chronic endometritis in females with endometriosis.

1 cl, 3 dwg, 4 ex

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RU 2 731 413 C1

Authors

Orazov Mekan Rakhimberdyevich

Krasnopolskaia Kseniia Vladislavovna

Mikhaleva Liudmila Mikhailovna

Khamoshina Marina Borisovna

Volkova Snezhana Vladimirovna

Khovanskaia Tatiana Nikolaevna

Shustova Viktoriia Borisovna

Abitova Marianna Zaurbievna

Dates

2020-09-02Published

2020-05-17Filed