SULPHONAMIDE COMPOUND OR SALT THEREOF Russian patent published in 2020 - IPC C07D249/04 C07D271/10 A61K31/4245 A61K31/428 A61P35/00 

Abstract RU 2732572 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to a novel sulphonamide compound of formula (I) having inhibiting ribonucleotide reductase activity, and to pharmaceutical compositions containing it as an active ingredient.

[Formula 1]

EFFECT: obtaining novel compounds having ribonucleotide reductase inhibitory activity, which can be used as an antitumour agent, where the tumor is selected from a group, consisting of breast cancer, stomach cancer, lung cancer, pancreatic cancer, Ewing's sarcoma, glioblastoma, liver cancer, mesothelioma, prostate cancer, ovarian cancer, kidney cancer, colon and rectal cancer, melanoma and blood cancer.

31 cl, 4 dwg, 21 tbl, 354 ex

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RU 2 732 572 C2

Authors

Miyahara, Seiji

Ueno, Hiroyuki

Hara, Shoki

Ogino, Yoshio

Dates

2020-09-21Published

2017-05-30Filed