TRISPECIFIC BINDING MOLECULES FOR TREATING VIRAL HEPATITIS B INFECTION AND BOUND STATES Russian patent published in 2020 - IPC C07K16/46 C07K19/00 C12N5/10 C12N5/783 C12N15/09 A61K39/395 A61P31/20 

Abstract RU 2733496 C2

FIELD: biotechnology.

SUBSTANCE: invention refers to producing a molecule specifically bound to HBsAg, CD3 and CD28, and can be used in medicine.

EFFECT: obtained binding molecule consists of two polypeptides with SEQ ID NO: 43 and SEQ ID NO: 44, interconnected by leucine zipper, and can be used for effective treatment or prevention of HVB infection or condition caused by said HVB infection.

4 cl, 9 dwg, 4 ex

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RU 2 733 496 C2

Authors

Protzer, Ulrike

Bohne, Felix

Quitt, Oliver

Momburg, Frank

Moldenhauer, Gerhard

Dates

2020-10-02Published

2016-03-16Filed