FIELD: medicine.
SUBSTANCE: presented is an immune-inducing agent containing as an active ingredient at least one polypeptide having an immuno-inducing activity, or a recombinant vector containing a polynucleotide, which encodes a polypeptide and is able to express said polypeptide in vivo. Disclosed is a method of producing an antigen-presenting cell comprising a complex of said polypeptide and MHC molecules, involving bringing said polypeptide into contact with an antigen-presenting cell of an individual ex vivo or in vitro. What is presented is a method for producing a cytotoxic T-cell specific for said polypeptide. Disclosed is a method of inducing immunity, comprising administering to an individual at least one polypeptide having an immuno-inducing activity or a recombinant vector containing a polynucleotide encoding a polypeptide, and capable of expressing said polypeptide in vivo.
EFFECT: presented group of inventions provides effective agents and methods for inducing immunity.
11 cl, 2 ex, 3 dwg
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Authors
Dates
2020-10-07—Published
2017-03-27—Filed