FIZZY COMPOSITIONS BASED ON ORNITHINE ASPARTATE Russian patent published in 2020 - IPC A61K9/00 A61K9/16 A61K9/20 A61K9/46 A61K31/198 A61K38/08 A61K47/02 A61K47/12 A61J3/10 

FIELD: pharmaceutical industry.

SUBSTANCE: group of inventions relates to a method for making fizzy composition based on ornithine aspartate, according to which is granulated mixture containing ornithine aspartate and gas-forming component, which is sodium bicarbonate, to obtain G granules; then G granules are mixed with sweetener and with at least one component, which is a pharmaceutically acceptable polybasic organic acid or a partial salt thereof with alkali or alkali-earth metals, to obtain said fizzy composition. Also disclosed are: a pharmaceutical fizzy composition based on ornithine aspartate obtained using the disclosed method, and a medicinal oral form selected from a tablet, pellet or sachet containing the disclosed fizzy composition.

EFFECT: group of inventions provides improved stability of the composition with respect to chemical decomposition during its manufacturing and/or storage and, as a result, fewer impurities.

9 cl, 19 tbl, 4 dwg