FASTING MIMICKING DIET (FMD), AND GLUCOSE-LOWERING DRUGS, PROTECTING NORMAL CELLS AND CREATING CONDITIONS OF CANCER SENSITIZATION IN RESPONSE TO STANDARD CONDITIONS AND CONDITIONS WITH HIGH CONTENT OF GLUCOSE INDUCED BY RAPAMYCIN AND DEXAMETHASONE Russian patent published in 2020 - IPC A61K31/436 A61K31/573 A61P3/10 

Abstract RU 2734774 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: group of inventions relates to methods of protecting normal tissues from high toxicity/sensitization to chemotherapeutic drugs induced by high blood glucose levels. Disclosed are methods (versions) of treating hyperglycemia in a subject undergoing chemotherapy, or eliminating sensitization to chemotherapy associated with high glucose levels, wherein methods include identifying a subject undergoing chemotherapy and receiving a hyperglycemia-inducing agent, and short-term fasting (STS) or diet abstinence (FMD) diet assignment to a subject, for a period of time from 3 to 10 days, where the hyperglycemic inducing agent is selected from a group, consisting of rapamycin, steroid medicinal preparations, including dexamethasone, and their combinations.

EFFECT: group of inventions provides reducing side effects associated with chemotherapy.

12 cl, 6 dwg, 1 tbl, 1 ex

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RU 2 734 774 C2

Authors

Longo Valter D.

Di Biaze Stefano

Dates

2020-10-23Published

2016-04-18Filed