DERIVED FROM HUMAN THROMBOCYTE LYSATE, EXTRACELLULAR VESICLES FOR USE IN MEDICINE Russian patent published in 2020 - IPC A61K35/19 A61P37/06

Abstract RU 2735139 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: first object is a pharmaceutical composition containing a fraction enriched with extracellular vesicles, obtained from human thrombocyte lysate, for use in treating or preventing diseases responding to immune system modulation. Second object is a method for preparing the corresponding pharmaceutical composition, involving the steps of: obtaining human thrombocyte lysate from donor thrombocytes; recovering extracellular vesicles derived from human thrombocyte lysate, and enriching the obtained fraction; determining in vitro immunomodulatory effect of said extracellular vesicles; selecting enriched extracellular vesicles; said enriched extracellular vesicles are mixed with a suitable pharmaceutical excipient and/or carrier.

EFFECT: technical result consists in immunomodulating effect of pharmaceutical composition containing fraction enriched with extracellular vesicles, obtained from human thrombocyte lysate.

16 cl, 5 ex

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RU 2 735 139 C2

Authors

De Miroshedzhi, Kira Nataliya Matakhari

Dates

2020-10-28—Published

2017-06-07—Filed