COPOLYMER AND SEPARATION MEMBRANE, A MEDICAL DEVICE AND A BLOOD PURIFICATION APPARATUS USING SAID COPOLYMER Russian patent published in 2020 - IPC C08F218/04 A61M1/36 B01D39/16 B01D61/00 

FIELD: medicine.

SUBSTANCE: present invention relates to a copolymer, a separating membrane, a medical device and a blood purification device. Said copolymer includes two or more types of monomer links, which are a hydrophobic monomer link and a hydrophilic monomer link. Hydrophobic monomer unit is a repeating link in a homopolymer or copolymer obtained by polymerisation of monomers, selected from a group consisting of vinyl carboxylate, methacrylate, acrylate and styrene derivative. Hydrophilic monomer link is a repeating link in a homopolymer or copolymer obtained by polymerising monomers selected from a group consisting of N-vinylamide, an acrylamide derivative, a methacrylamide derivative, N-vinyl lactam and N-acryloyl morpholine. Number-average molecular weight of the copolymer ranges from 2,000 to 1,000,000. Specific energy of hydration of copolymer ranges from 158.992 to 209.200 kJ·mol^-1·nm^-3. Monomer link with the highest specific hydration energy of the monomeric link i is a monomer link not containing a hydroxyl group. Volume fraction of the monomeric link with the highest specific energy of hydration of the monomeric link i ranges from 35 to 90 %. Difference in specific energy of hydration ranges from 71.128 to 418.400 kJ·mol^-1·nm^-3. Specific energy of hydration (cal·mol^-1·Å^-3) of copolymer is integer from 1 to N, where N is total number of types of monomers, which form a copolymer and i.

EFFECT: technical result is the development of a copolymer containing two or more types of monomer links, and specific energy of hydration of the copolymer and a monomer link forming a copolymer, which is able to prevent adhesion of proteins and thrombocytes, and can maintain high water permeability even in contact with a biological component, such as blood for a long period of time.

6 cl, 2 tbl, 24 ex, 1 dwg