FIELD: medicine.
SUBSTANCE: group of inventions can be used for treating or preventing primary biliary cholangitis in a patient. For this purpose, in the manufacture of a medicament, compound 2-[(1R,3r,5S)-3-({5-cyclopropyl-3-[2-(trifluoromethoxy)phenyl]-1,2-oxazol-4-yl}methoxy)-8-azabicyclo[3.2.1]octan-8-yl]-4-fluoro-1,3-benzothiazole-6-carboxylic acid. Said compound is administered in dose of 10 mcg. Also disclosed are application of said agent in doses of 30 mcg, 60 mcg, 90 mcg, 100 mcg.
EFFECT: group of inventions provides treating, as well as preventing primary biliary cholangitis in a patient.
5 cl, 5 tbl, 2 dwg, 5 ex
| Title |
Year |
Author |
Number |
| FXR AGONISTS APPLICATION METHODS |
2017 |
- Laffitte, Bryan
- Badman, Michael
- Chen, Jin
- Lindgren, Sam
|
RU2743075C2 |
| TREATMENT OF INTRAHEPATIC CHOLESTATIC DISEASES |
2017 |
- Baudes Pol
- Makuerter Charlz A.
|
RU2765460C2 |
| METHODS FOR INCREASING HEIGHT OF PEDIATRIC PATIENTS WITH CHOLESTATIC LIVER DISEASE |
2020 |
- Jaecklin, Thomas
- Dorenbaum, Alejandro
|
RU2822484C2 |
| METHODS OF TREATING CHOLESTASIS |
2020 |
- Jaecklin, Thomas
- Dorenbaum, Alejandro
|
RU2829466C2 |
| DEUTERATED DERIVATIVE OF CHENODEOXYCHOLIC ACID AND PHARMACEUTICAL COMPOSITION CONTAINING SAID COMPOUND |
2016 |
- Lv, Binhua
- Sheng, Zelin
- Li, Chengwei
|
RU2712033C2 |
| METHODS FOR MODULATING BILE ACID HOMEOSTASIS AND TREATMENT OF BILE ACID DISORDERS AND DISEASES |
2013 |
|
RU2675514C2 |
| TREATMENT OF CHOLESTATIC ITCHING |
2018 |
- Boudes, Pol
- Mcwherter, Charles, A.
- Steinberg, Alexandra, S.
|
RU2781281C2 |
| CRYSTALLINE OR AMORPHOUS FORM OF FXR AGONISTS BEING STEROID DERIVATIVES, THEIR PRODUCTION METHOD AND THEIR USE |
2018 |
- Li, Syaolin
- Syao, Khualin
- Li, Pen
- Khe, Khajin
- Li, Vejdun
|
RU2800751C2 |
| BENZOTHIA(DI)AZEPINE COMPOUNDS AND USE THEREOF AS BILE ACID MODULATORS |
2020 |
- Gillberg Per-Goran
- Starke Ingemar
- Kulkarni Santosh S.
|
RU2837840C1 |
| BENZOTHIADIAZEPINE COMPOUNDS AND USE THEREOF AS BILE ACID MODULATORS |
2020 |
- Gillberg Per-Goran
- Starke Ingemar
- Kulkarni Santosh S.
|
RU2838136C1 |
