FIELD: medicine.
SUBSTANCE: group of inventions relates to detection of Lyme disease and other diseases transmitted by ticks. Disclosed is a solid substrate for detecting the presence of antibodies in a biological sample, containing microbial antigens immobilized on said solid substrate, comprising at least one antigen obtained from a group consisting of pleomorphic round bodies of genus Borrelia, wherein said Borrelia species is selected from a group consisting of Borrelia afzelii and Borrelia garinii, and said antigen is a lysate of said pleomorphic round bodies of genus Borrelia. Also disclosed is a method for detecting antibodies in a biological sample and using said solid support for making a diagnostic test.
EFFECT: group of inventions provides creating a new platform that enables distinguishing acute, past, chronic and persistent stages of diseases transmitted by mites.
19 cl, 7 dwg, 1 tbl, 1 ex
| Title |
Year |
Author |
Number |
| NUCLEOTIDE SEQUENCE ENCODING THE DBPAG POLYPEPTIDE, ADVANTAGEOUS FOR SERODIAGNOSIS OF LYME BORRELIOSIS, PETDBPAGNH RECOMBINANT PLASMID DNA, ENCODING DBPAG COMBINED POLYPEPTIDE, RECOMBINANT BACTERIA STRAIN ESCHERICHIA COLI BL21(DE3)/PETDBPAGNH - PRODUCER OF DBPAG POLYPEPTIDE, DBPAG POLYPEPTIDE AND METHOD FOR PREPARATION THEREOF |
2017 |
- Panfertsev Evgenij Aleksandrovich
- Baranova Evgeniya Vladimirovna
- Mochalov Vladimir Vyacheslavovich
- Biketov Sergej Fedorovich
- Solovev Pavel Vladimirovich
- Gorbatov Aleksej Aleksandrovich
|
RU2681229C1 |
| RECOMBINANT CHIMERIC POLYPEPTIDES, CARRYING EPITOPES OF VARIOUS IMMUNODOMINANT PROTEINS OF SPIROCHAETA OF BORRELIA BURGDORFERI SENSU LATO COMPLEX, AND SERUM DIAGNOSTIC TECHNIQUE FOR IXODIC TICK-BORNE BORRELIOSIS |
2012 |
- Beklemishev Anatolij Borisovich
- Rjabchenko Aleksandr Vladimirovich
- Karavaev Vitalij Semenovich
|
RU2514230C1 |
| UNIVERSAL VACCINE FOR TREATING AND PREVENTING LYME DISEASE APPLICABLE IN HUMAN AND VETERINARY SCIENCE, AND METHOD FOR PREPARING IT |
2008 |
- Vrzal Vladimir
- Bittner Libor
- Nepereni Irzhi
- Khumela Josef
|
RU2472525C2 |
| BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION |
2010 |
- Leve, Lionel'
- Mezhan-Leturner, Odil'
|
RU2549698C2 |
| CHIMERIC PROTEIN USED FOR LYME-BORRELIOSIS DIAGNOSTICS |
2010 |
- Leve, Lionel'
- Mezhan-Leturner, Odil'
|
RU2546246C2 |
| VACCINE AGAINST LYME DISEASE IN DOGS |
2018 |
- Lafleur, Rhonda, L
- Dant, Jennifer, C
- Mogler, Mark, A
- Callister, Steven, M
- Xu, Zhichang
|
RU2785620C2 |
| RECOMBINANT PLASMID DNA PROVIDING SYNTHESIS OF BORRELIA GARINII IMMUNODOMINANT PROTEIN FOR LYME-BORRELIOSIS DIAGNOSIS |
2003 |
- Beklemishev A.B.
- Ivanov I.D.
|
RU2260047C2 |
| COMPOSITIONS AND METHODS FOR DIAGNOSING LYME DISEASE AND PREDICTING ELIMINATION OF LYME DISEASE-CAUSING SPIROCHETES AFTER TREATMENT |
2016 |
- Callister, Steven M.
- Boyle, Jeff
- Miyamasu, Misato
- Dattwyler, Raymond J.
- Arnaboldi, Paul M.
|
RU2750040C2 |
| SET OF REAGENTS FOR THE DETECTION OF PATHOGENS OF TICK-BORNE BORRELIOSIS |
2021 |
- Komarovskii Iurii Iurevich
- Gorbenko Aleksei Sergeevich
- Olkhovskii Igor Alekseevich
- Stoliar Marina Aleksandrovna
- Vasileva Daria Ivanovna
|
RU2763595C1 |
| OspA CHIMERIC GENES, PROTEINS, AND METHODS FOR THEIR USE |
2011 |
- Krou Brajan A.
- Livi Ian
- O'Rurk Mariya
- Shvendinger Mikhel
|
RU2636455C2 |
