BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION Russian patent published in 2015 - IPC C07K14/20 C07K19/00 C12N15/31 C12N15/63 G01N33/53 A61K39/116 

FIELD: medicine, pharmaceutics.

SUBSTANCE: presented group of inventions concerns fused proteins, nucleic acids coding these proteins, an expressing cartridge providing nucleic acid expression, a vector comprising this cartridge, a diagnostic technique for in vitro borreliosis, a kit for this diagnostic technique, which use these proteins, as well as a vaccine composition for preventing borreliosis containing these proteins. The characterised fused proteins contain (i) at least one sequence of DbpA protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii, and (ii) least one sequence of OspC protein of the species Borrelia specified in B. afzelii, B. burgdorferi sensu stricto and B. garinii.

EFFECT: presented group of inventions enables performing more sensitive and specific analyses related to the presence of certain pathogenic species Borrelia.

11 cl, 8 tbl, 7 ex