FIELD: medicine.
SUBSTANCE: invention refers to medicine, and concerns a universal vaccine for treating and preventing Lyme disease to be applied in veterinary science, based on a whole-cell bacterial vaccine or bacterial lysates or purified preparations, containing the three most pathogenic genospecies Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii, each of which simultaneously contains both immunogenic protective proteins of the outer membranes OspA and OspC.
EFFECT: invention provides developing the protective immunity against a natural tick-borne infection of the three most pathogenic genospecies Borrelia burgdorferi sensu stricto, Borrelia afzelii and Borrelia garinii.
9 cl, 1 ex, 12 tbl
| Title |
Year |
Author |
Number |
| BORRELIA HYBRID PROTEIN, NUCLEIC ACID CODING THIS PROTEIN, EXPRESSING CARTRIDGE, VECTOR, METHOD AND KIT FOR DIAGNOSING LYME BORRELIOSIS, VACCINE FOR BORRELIOSIS PREVENTION |
2010 |
- Leve, Lionel'
- Mezhan-Leturner, Odil'
|
RU2549698C2 |
| RECOMBINANT CHIMERIC POLYPEPTIDES, CARRYING EPITOPES OF VARIOUS IMMUNODOMINANT PROTEINS OF SPIROCHAETA OF BORRELIA BURGDORFERI SENSU LATO COMPLEX, AND SERUM DIAGNOSTIC TECHNIQUE FOR IXODIC TICK-BORNE BORRELIOSIS |
2012 |
- Beklemishev Anatolij Borisovich
- Rjabchenko Aleksandr Vladimirovich
- Karavaev Vitalij Semenovich
|
RU2514230C1 |
| NUCLEOTIDE SEQUENCE ENCODING THE DBPAG POLYPEPTIDE, ADVANTAGEOUS FOR SERODIAGNOSIS OF LYME BORRELIOSIS, PETDBPAGNH RECOMBINANT PLASMID DNA, ENCODING DBPAG COMBINED POLYPEPTIDE, RECOMBINANT BACTERIA STRAIN ESCHERICHIA COLI BL21(DE3)/PETDBPAGNH - PRODUCER OF DBPAG POLYPEPTIDE, DBPAG POLYPEPTIDE AND METHOD FOR PREPARATION THEREOF |
2017 |
- Panfertsev Evgenij Aleksandrovich
- Baranova Evgeniya Vladimirovna
- Mochalov Vladimir Vyacheslavovich
- Biketov Sergej Fedorovich
- Solovev Pavel Vladimirovich
- Gorbatov Aleksej Aleksandrovich
|
RU2681229C1 |
| CHIMERIC PROTEIN USED FOR LYME-BORRELIOSIS DIAGNOSTICS |
2010 |
- Leve, Lionel'
- Mezhan-Leturner, Odil'
|
RU2546246C2 |
| RECOMBINANT PLASMID DNA PROVIDING SYNTHESIS OF BORRELIA GARINII IMMUNODOMINANT PROTEIN FOR LYME-BORRELIOSIS DIAGNOSIS |
2003 |
- Beklemishev A.B.
- Ivanov I.D.
|
RU2260047C2 |
| VACCINE AGAINST LYME DISEASE IN DOGS |
2018 |
- Lafleur, Rhonda, L
- Dant, Jennifer, C
- Mogler, Mark, A
- Callister, Steven, M
- Xu, Zhichang
|
RU2785620C2 |
| METHOD AND A SOLID SUPPORT FOR DETECTING TICK-BORNE MICROORGANISMS IN A BIOLOGICAL SAMPLE |
2017 |
- Gilbert Leona
- Garg Kunal
- Merilainen Leena
- Puttaraksa Kanoktip
|
RU2737896C2 |
| SET OF REAGENTS FOR THE DETECTION OF PATHOGENS OF TICK-BORNE BORRELIOSIS |
2021 |
- Komarovskii Iurii Iurevich
- Gorbenko Aleksei Sergeevich
- Olkhovskii Igor Alekseevich
- Stoliar Marina Aleksandrovna
- Vasileva Daria Ivanovna
|
RU2763595C1 |
| OspA CHIMERIC GENES, PROTEINS, AND METHODS FOR THEIR USE |
2011 |
- Krou Brajan A.
- Livi Ian
- O'Rurk Mariya
- Shvendinger Mikhel
|
RU2636455C2 |
| OSPA CHIMERIC GENES, PROTEINS AND METHODS FOR USE THEREOF |
2011 |
- Krou Brajan A.
- Livi Ian
- O'Rurk Marija
- Shvendinger Mikhel
- Dann Dzhon Dzh.
- Laft Bendzhamin Dzh.
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RU2583289C2 |
