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(19)

RU

(11)

2 805 674

(13)

C2

(51)

IPC

C07K16/46(2006-01-01)

C07K14/705(2006-01-01)

C07K16/28(2006-01-01)

C07K19/00(2006-01-01)

C12N15/13(2006-01-01)

C12N15/62(2006-01-01)

C12N5/10(2006-01-01)

A61K35/17(2015-01-01)

A61P37/06(2006-01-01)

(21) (22)

Application

2020112262, 2018-09-20

(24)

Start date

2018-09-20

(22)

Actual filing date

2018-09-20

(45)

Published

2023-10-23

(72)

Inventor

Zhou, LiAbel, TobiasMeyer, FrancoisLevings, MeganDawson, NicolasLamarche, Caroline

(73)

Holder

The University Of British ColumbiaSangamo Therapeutics France

NEW ANTI-HLA-A2 ANTIBODIES AND THEIR APPLICATION Russian patent published in 2023 - IPC C07K16/46 C07K14/705 C07K16/28 C07K19/00 C12N15/13 C12N15/62 C12N5/10 A61K35/17 A61P37/06 

Abstract RU 2805674 C2

FIELD: biotechnology; medicine.

SUBSTANCE: invention discloses a novel anti-human leukocyte antigen A2 (HLA-A2) antibody and a chimeric antigen receptor (CAR) containing said anti-HLA-A2 antibody.

EFFECT: regulatory immune cells expressing the CARs of the present invention may be useful for treating or preventing transplant rejection or graft-versus-host disease (GVHD).

22 cl, 1 ex, 1 dwg

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RU 2 805 674 C2

Authors

Zhou, Li

Abel, Tobias

Meyer, Francois

Levings, Megan

Dawson, Nicolas

Lamarche, Caroline

Dates

2023-10-23—Published

2018-09-20—Filed

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