POLYMER MATERIAL (HYDROGEL) BASED ON BACTERIAL ALGINATE FOR PLACING PROBIOTIC BACTERIA AND METHOD FOR PRODUCTION THEREOF Russian patent published in 2021 - IPC C12N1/04 C12N11/02 A61K47/36 A61K35/74 

Abstract RU 2740086 C1

FIELD: biotechnology.

SUBSTANCE: group of inventions relates to biotechnology. Disclosed are polymer material for arrangement of probiotic bacteria based on bacterial alginate, produced by bacteria of genus Azotobacter, and method of its production. Method includes growth of A. chroococcum and A. vinelandii bacteria biomass in Burke liquid medium, biomass mixing with 50 mM EDTA solution in 0.9 wt. % NaCl, precipitation with 96 % ethyl alcohol and purification. Bacterial alginate solution is further gelated in an aqueous solution of 50 ± 1 mM calcium chloride for 10 ± 1 min.

EFFECT: inventions provide preparing a biologically active material for regenerative medicine in treating gastrointestinal diseases.

5 cl, 4 ex, 1 dwg

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RU 2 740 086 C1

Authors

Bonartsev Anton Pavlovich

Voinova Vera Vladimirovna

Bonartseva Garina Aleksandrovna

Dates

2021-01-11Published

2019-12-13Filed