FIELD: biotechnology.
SUBSTANCE: invention represents a method for enhancing feline umami receptor activity, comprising contacting a composition comprising an amino acid and a nucleotide or nucleotide derivative, with feline umami receptor, wherein the composition interacts in a site of interaction of the feline umami receptor with one or more amino acids selected from a group consisting of Ser172, Thr149, Thr148, Glu301, Tyr220, Glu170, Asp302, His71, Arg277, His308, Ser306, Ser384, Ala380, His47, Asn69, Asp302, Met383, Ser385, Ile309, Ser107, Asp49 and combinations thereof.
EFFECT: methods for modulation of taste receptors are proposed.
28 cl, 84 dwg, 27 tbl, 9 ex
| Title | Year | Author | Number |
|---|---|---|---|
| TASTE-AND-FLAVOR COMPOSITIONS AND FOOD PRODUCTS FOR DOMESTIC ANIMALS CONTAINING THEM | 2015 |
|
RU2727651C2 |
| COMPOUNDS MODULATING THE ACTIVITY OF CALCIUM-SENSITIVE RECEPTORS FOR MODULATING THE KOKUMI TASTE, AND FEED PRODUCTS FOR PETS, CONTAINING SAID COMPOUNDS | 2017 |
|
RU2759563C2 |
| COMPOUNDS THAT MODULATE ACTIVITY OF GPR92 RECEPTORS AND PET FOOD PRODUCTS CONTAINING THEM | 2019 |
|
RU2807217C2 |
| COMPOUNDS HAVING BOUND HETEROARYL FRAGMENTS AND USE THEREOF AS NOVEL UMAMI TASTE MODIFIERS, TASTANTS (TASTE BUD CELL STIMULANTS) AND TASTE BOOSTERS IN FOOD COMPOSITIONS | 2006 |
|
RU2410383C2 |
| NOVEL AROMATISING SUBSTANCES, TASTE MODIFIERS, FLAVOURING COMPOUNDS, TASTE BOOSTERS, UMAMI OR SWEET TASTE ENDOWING COMPOUNDS, AND/OR BOOSTERS AND USE THEREOF | 2004 |
|
RU2419602C2 |
| NEW VARIANT OF GLUTAMINE HYDROLYZING GMP SYNTHASE AND A METHOD OF PRODUCING PURINE NUCLEOTIDE USING IT | 2021 |
|
RU2804010C1 |
| NEW ADENYL-SUCCINATE SYNTHETASE AND METHOD FOR PRODUCING PURINE NUCLEOTIDES USING IT | 2018 |
|
RU2770464C1 |
| PEPTIDES HAVING AGONISTIC ACTIVITY ON NEUROPEPTIDE-2 RECEPTOR (Y2R) | 2006 |
|
RU2383553C2 |
| FLAVOURING ADDITIVES | 2013 |
|
RU2639888C2 |
| DISPLAY OF AN INTEGRAL MEMBRANE PROTEIN ON EXTRACELLULAR ENVELOPED POXVIRUS VIRIONS | 2017 |
|
RU2759846C2 |
