FIELD: medicine.
SUBSTANCE: invention refers to medicine and can be used for prediction of developing cardiotoxicity in HER2 patients with positive breast cancer of initially low / moderate cardiovascular risk receiving a targeted therapy with trastuzumab after anthracycline-containing chemotherapy. That is ensured by echocardiography with determination of total longitudinal LV deformation (GLS). Decrease in the given ≥10 % value after the termination of anthracycline-containing chemotherapy compared to the initial value indicates a high risk of developing cardiotoxicity in the therapy with trastuzumab.
EFFECT: invention enables assessing the risk of developing cardiotoxicity during therapy with trastuzumab in the above category of patients.
1 cl, 1 tbl, 2 ex
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