FIELD: medicine.
SUBSTANCE: invention refers to medicine, particularly to cardio-oncology and medical genetics, and aims at predicting subacute anthracycline-mediated cardiotoxicity in oncological patients. Method includes genotyping polymorphism rs28714259 on a DNA matrix extracted from blood or buccal epithelium. If genotypes G / A or A / A are present, a high risk of subacute anthracycline-mediated cardiotoxicity is predicted.
EFFECT: invention provides a cheap, easy-to-implement high-information method for predicting the risk of anthracycline-mediated cardiotoxicity in oncological patients before using anthracycline antibiotics.
1 cl, 4 tbl, 3 ex
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Authors
Dates
2021-03-15—Published
2020-07-27—Filed