METHOD FOR PREDICTION OF SUBACUTE ANTHRACYCLINE-MEDIATED CARDIOTOXICITY DEVELOPMENT IN ONCOLOGICAL PATIENTS Russian patent published in 2021 - IPC G01N33/50 C12Q1/68 

Abstract RU 2744682 C1

FIELD: medicine.

SUBSTANCE: invention refers to medicine, particularly to cardio-oncology and medical genetics, and aims at predicting subacute anthracycline-mediated cardiotoxicity in oncological patients. Method includes genotyping polymorphism rs28714259 on a DNA matrix extracted from blood or buccal epithelium. If genotypes G / A or A / A are present, a high risk of subacute anthracycline-mediated cardiotoxicity is predicted.

EFFECT: invention provides a cheap, easy-to-implement high-information method for predicting the risk of anthracycline-mediated cardiotoxicity in oncological patients before using anthracycline antibiotics.

1 cl, 4 tbl, 3 ex

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RU 2 744 682 C1

Authors

Gvaldin Dmitrij Yurevich

Timoshkina Natalya Nikolaevna

Omelchuk Ekaterina Petrovna

Vashchenko Larisa Nikolaevna

Ratieva Anastasiya Sergeevna

Vladimirova Lyubov Yurevna

Storozhakova Anna Eduardovna

Svetitskaya Yana Vladimirovna

Tikhanovskaya Natalya Mikhajlovna

Novikova Inna Arnoldovna

Dates

2021-03-15Published

2020-07-27Filed