METHOD FOR PREDICTING THE COURSE OF LOW-DIFFERENTIATED GLIAL TUMORS BASED ON A CYTOKINE MICROENVIRONMENT Russian patent published in 2021 - IPC G01N33/574 

FIELD: medicine.

SUBSTANCE: invention relates to medicine and concerns a method for predicting the course of low-grade glial tumors based on a cytokine microenvironment, consisting in the fact that in the tumor tissue by the immunoenzymometric analysis the complex content of interleukins IL-4, IL-6, IL-8 is determined, and with their total IL-4 content within 0.5 to 1.4 pg/ml/g of protein, IL-6 from 4.4 to 50.6 pg/ml/g of protein, IL-8 from 43.7 to 125.2 pg/ml/g of protein predicted early tumor progression within 7-14 months after operation, and with their total content of IL-4 ranging from 13.1 to 28.2 pg/ml/g protein, IL-6 from 0 to 8.2 pg/ml/g protein, IL-8 from 0.3 to 19.6 pg/ml/g of the protein, progression is predicted more than 14 months after the operation.

EFFECT: invention provides predicting the course of low-grade glial tumors based on their cytokine microenvironment.

1 cl, 2 ex