ONCOBOX GENETIC INFORMATION ANALYSIS PLATFORM Russian patent published in 2021 - IPC G01N33/15 C12N5/09 G16H10/40 

Abstract RU 2741703 C1

FIELD: medicine.

SUBSTANCE: proposed group of inventions relates to medicine. Presented is a method for evaluating the clinical effectiveness of the targeted medicines for treating a patient with a proliferative or oncological disease, in which data of at least one type from the sample are obtained, wherein the data type is selected from the following list: (i) data on total mRNA expression, (ii) full genome data on protein expression, (iii) full genome data on binding sites of transcription factors, (iv) full genome data on mutations in genomic DNA, (v) full genome data on microRNA expression. Disclosed is a method of treating a patient with a proliferative or oncological disease and a system for assessing the clinical effectiveness of targeted therapeutics, selected from a group of targeted drugs, for a patient with proliferative or oncological tissue disease.

EFFECT: presented group of inventions enables effective clinical effectiveness evaluation of existing targeted medicinal agents for individual patient with proliferative or oncological disease.

6 cl, 10 dwg, 8 tbl, 8 ex

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RU 2 741 703 C1

Authors

Buzdin Anton Aleksandrovich

Sorokin Maksim Igorevich

Tkachev Viktor Sergeevich

Nikitin Daniil Mikhailovich

Zolotovskaia Marianna Arsenovna

Garazha Andrei Vladimirovich

Borisov Nikolai Mikhailovich

Dates

2021-01-28Published

2018-03-01Filed