FIELD: pharmaceuticals.
SUBSTANCE: invention relates to use of a compound of formula (I) or its diastereomer, enantiomer, salt, solvate or solvate of salts, wherein R1 represents C1-C6-alkyl, wherein C1-C6 alkyl group is unsubstituted or mono- or polysubstituted identically or differently by halogen, hydroxyl, unsubstituted or mono- or poly-halogen-substituted C3-C6-cycloalkyl, or a group R6, R7SO2, R7 SO or R8O, or a group selected from: 
, R2 and R3 always have the same definition and both are either hydrogen or C1-C6-alkyl; R4 is halogen, cyano, unsubstituted or mono- or multiple-substituted or identically substituted with C1-C6-alkyl or unsubstituted or singly or multiple identical or differently substituted C3-C6-cycloalkyl, and substitutes are selected from a group of halogen and hydroxyl; R5 denotes hydrogen, halogen or unsubstituted or mono- or poly-halogen-substituted C1-C6-alkyl; R6 is an unsubstituted or mono- or di-methyl-substituted monocyclic saturated heterocycle with 4–6 ring atoms, which contains a heteroatom or a hetero group from the group of O, S, SO and SO2; R7 represents C1-C6-alkyl, wherein C1-C6 alkyl group is unsubstituted or mono- or polysubstituted identically or differently by halogen, hydroxyl or C3-C6-cycloalkyl; or R7 is C3-C6-cycloalkyl; R8 represents C1-C6-alkyl, wherein C1-C6 alkyl group is unsubstituted or mono- or polysubstituted identically or differently by halogen. Invention also relates to a medicinal agent containing a compound of formula (I), which inhibits interleukin-1 receptor-associated kinase 4 (IRAK4).
EFFECT: technical result is a novel use of the compound of formula (I), which can be used in veterinary science for treating and/or preventing allergic and/or inflammatory IRAK4 related diseases in animals.
27 cl, 13 dwg, 6 tbl, 22 ex
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