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2 720 510

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IPC

C07D215/42(2006-01-01)

C07D311/12(2006-01-01)

C07D311/14(2006-01-01)

C07D335/06(2006-01-01)

A61K31/37(2006-01-01)

A61K31/382(2006-01-01)

A61K31/4704(2006-01-01)

A61P25/28(2006-01-01)

(21) (22)

Application

2017123588, 2017-07-04

(24)

Start date

2017-07-04

(22)

Actual filing date

2017-07-04

(45)

Published

2020-04-30

(72)

Inventor

Mokrov Grigorij VladimirovichLitvinova Svetlana AleksandrovnaNerobkova Lyubov NikolaevnaKovalev Ivan GeorgievichGudasheva Tatyana AleksandrovnaVoronina Tatyana AleksandrovnaDurnev Andrej DmitrievichSeredenin Sergej Borisovich

(73)

Holder

Federalnoe Gosudarstvennoe Byudzhetnoe Nauchnoe Uchrezhdenie Institut Farmakologii Imeni V.V. Zakusova"

COUMARIN, THIOCOUMARIN AND QUINOLINONE DERIVATIVES, HAVING ANTICONVULSANT ACTIVITY Russian patent published in 2020 - IPC C07D215/42 C07D311/12 C07D311/14 C07D335/06 A61K31/37 A61K31/382 A61K31/4704 A61P25/28

Abstract RU 2720510 C2

FIELD: medicine; pharmaceuticals.

SUBSTANCE: invention relates to derivatives of (coumarin-4-yl) aminocarboxylic acids, (thiocoumarin-4-yl) aminocarboxylic acids and (2-oxo-1,2-dihydroquinolin-4-yl) aminocarboxylic acids. In formulas 1.1–1.3, R is hydrogen or a nitro group; X is O, S or NH; Y is OH, OCH₃, OC₂H₅, NH₂ or NHCH₃. Invention also relates to methods for preparing said compounds and a method of treating epilepsy and paroxysmal conditions using said compounds.

EFFECT: can be used in treating epilepsy and paroxysmal conditions.

13 cl, 5 tbl, 13 ex

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RU 2 720 510 C2

Authors

Mokrov Grigorij Vladimirovich

Litvinova Svetlana Aleksandrovna

Nerobkova Lyubov Nikolaevna

Kovalev Ivan Georgievich

Gudasheva Tatyana Aleksandrovna

Voronina Tatyana Aleksandrovna

Durnev Andrej Dmitrievich

Seredenin Sergej Borisovich

Dates

2020-04-30—Published

2017-07-04—Filed