FIELD: biotech.
SUBSTANCE: invention relates to a new strain of foot and mouth disease Aphtae epizooticae of Asia 1 type, Picornaviridae family, genus Aphthovirus, deposited in the collection of FSBI "ARRIAH" under registration number: No 176 - dep / 19-66 - GKShM FSBI "ARRIAH" strain Asia-1 No 2356 / 14/2018 of FMD virus. The presented strain is reproduced in continuous cultures of kidney cells of the Siberian mountain ibex (PSGK-30), in a continuous culture of pig kidney cells IB-RS-2 and in a continuous culture of kidney cells of the Syrian hamster BHK - 21, within 20-24 hours of incubation; virus yield, assessed by the cytopathic effect in these cell cultures, reaches values from 5.25-7.00 lg TCD50/cm3, maintaining the original characteristics when passaged in cell cultures for 5-10 passages. EFFECT: presented strain can be used to control the antigenic activity of FMD vaccines and for the manufacture of biological products for the diagnosis and specific prevention of FMD of Asia 1 type.
1 cl, 1 dwg, 6 tbl
| Title | Year | Author | Number |
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| STRAIN O N 2356/PAKISTAN/2018 FOOT-AND-MOUTH DISEASE VIRUS APHTAE EPIZOOTICAE GENOTYPE O/ME-SA/PANASIA2 FOR THE MANUFACTURE OF BIOPREPARATIONS FOR THE DIAGNOSIS OF FOOT-AND-MOUTH DISEASE | 2023 |
|
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| INACTIVATED SORBED VACCINE AGAINST FMD OF TYPE A | 2014 |
|
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| STRAIN O N 2311/ZABAIKALSKY/2016 FOOT AND MOUTH DISEASE VIRUS TYPE APHTAE EPIZOOTICAE TYPE O FOR MANUFACTURING OF BIOLOGICS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF FOOT AND MOUTH DISEASE OF TYPE O | 2017 |
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| A N2269/VNIIZZH/2015 STRAIN OF TYPE A APHTAE EPIZOOTICAE FOOT-AND-MOUTH DISEASE VIRUS FOR CONTROL OF ANTIGENIC AND IMMUNOGENIC ACTIVITY AND FOR MANUFACTURE OF BIOPREPARATIONS FOR DIAGNOSIS AND SPECIFIC PREVENTION OF TYPE A FOOT-AND-MOUTH DISEASE | 2016 |
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RU2553219C1 |
