IMMUNOGENIC COMPOSITION LHRH AND ITS USE IN SWINE Russian patent published in 2021 - IPC A61K39/00 C07K7/23 A61P15/00

Abstract RU 2745720 C2

FIELD: veterinary medicine.

SUBSTANCE: group of inventions refers to a veterinary composition for pig immunocastration and use thereof. Disclosed is a veterinary composition for pig immunocastration comprising (a) an effective amount of a mixture in equal molar ratios of peptide immunogens, having an amino acid sequence presented by SEQ ID NOs: 7, 8 and 9, in physiological saline; and (b) an acceptable veterinary drug delivery or adjuvant, selected from a group consisting of water, physiological solution, alum, incomplete Freund's adjuvant (IFA), liposin, saponin, squalene, L121, emulsigen, monophosphoryl lipid A (MPL), QS21, ISA 720, ISA 50, ISA 50V2, emulsion D, ISA 35, ISA 206, oils, lipids, polysorbate 80, emulsifiers, ethanol, polyol and any combinations thereof. Disclosed composition is used in a pig immunocastration method, with a testosterone reduction product in an animal, a method for inducing luteinizing hormone releasing hormone (LHRH) antibodies in a pig.

EFFECT: group of inventions provides high efficiency for immunocastration.

13 cl, 29 dwg, 18 tbl, 10 ex

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RU 2 745 720 C2

Authors

Wang, Chang, Yi

Peng, Wen-Jiun

Dates

2021-03-31—Published

2014-07-25—Filed