DERIVATIVE WITH CONDENSED RING AS A RECEPTOR INHIBITOR Russian patent published in 2021 - IPC C07D471/04 C07D513/04 C07D519/00 A61K31/00 A61K31/41 A61P35/00 

FIELD: chemistry.

SUBSTANCE: present invention relates to a compound represented by the formula (I) or a pharmaceutically acceptable salt thereof,

In the compound of the formula (I): 1 or 2 of T₁, T₂, T₃ and T₄ constitute N, wherein the rest independently constitute CH; each R₁ is independently selected from H, halogen, NH₂ or C_1-3alkyl optionally substituted with 1, 2 or 3 R; each R₂ is independently selected from H, halogen or C_1-3alkyl; n is selected from 0 and 1; m is selected from 0, 1 and 2; the ring A is selected from 5-10-membered heteroaryl; each "hetero" in the 5-10-membered heteroaryl is independently selected from N, S, and NH; the number of heteroatoms or heteroatomic groups in the 5-10-membered heteroaryl is independently selected from 1, 2 and 3; the ring B is selected from phenyl and 5-6-membered heteroaryl; each "hetero" in the 5-6-membered heteroaryl is independently selected from N, O, and S; the number of heteroatoms or heteroatomic groups in the 5-6-membered heteroaryl is independently selected from 1 and 2; R is selected from F, Cl, Br and I. Also proposed are specific compounds and application in manufacture of a medicinal product for treatment of a disease associated with the A_2A receptor.

EFFECT: new organic compounds of the formula (I) constituting antagonists of an adenosine receptor A_2A are proposed.

17 cl, 4 ex, 7 tbl