METHOD FOR OBTAINING QUATERNARY AMMONIUM SALT WITH ANTITUMOR ACTION Russian patent published in 2021 - IPC C07D487/18 A61K31/53 A61P35/00 

Abstract RU 2749722 C1

FIELD: organic chemistry.

SUBSTANCE: present invention relates to organic chemistry, namely to a method for producing 1-(1,3-dioxolanyl-2-methyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane bromide. The method involves the interaction of urotropin with 2-bromomethyl-1,3-dioxolane at a temperature of 60°C for 4 hours at the following ratio of components, mol%: urotropin - 50; 2-bromomethyl-1,3-dioxolane - 50.

EFFECT: invention is aimed at obtaining a compound 1-(1,3-dioxolanyl-2-methyl) -3,5,7-triaza-1-azoniatricyclo [3.3.1.13,7] decane bromide, which has antitumor activity.

1 cl, 1 tbl

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RU 2 749 722 C1

Authors

Zlotskij Semen Solomonovich

Raskildina Gulnara Zinurovna

Sakhabutdinova Gulnur Nazifullovna

Dates

2021-06-16Published

2020-07-15Filed