MOLDED CARBON SORBENT WITH GLYCOLIC ACID, A METHOD FOR ITS PREPARATION AND A METHOD FOR TREATING BACTERIAL VAGINOSIS Russian patent published in 2021 - IPC A61K31/215 A61K31/191 A61P15/02 B01J20/26 B01J20/28 B01J20/32 B82Y40/00 B01J20/20 B82B3/00 

FIELD: pharmacology.

SUBSTANCE: group of inventions relates to a molded carbon sorbent, its preparation and use in medicine as an applicator for the treatment of bacterial vaginosis. The modified sorbent is a molded mesoporous carbon sorbent of cylindrical shape and geometric dimensions: diameter 8-10 mm, length 45-60 mm, with one internal channel of circular cross-section, specific adsorption surface no more than 50 m²/g, crushing strength no less than 20 kg/cm², glycolic acid content in the form of polyglycolide of not less than 5 to 7.4, weight percentage. A method for manufacturing a molded sorbent is described, including impregnation of the initial molded sorbent with a 50% aqueous solution of glycolic acid for 24 hours at room temperature, the ratio of sorbent-modifier 1:2 by weight, followed by drying for an hour at 103-107°C and polycondensation of glycolic acid on a carbon molded sorbent in two stages: at a temperature of 190-200°C for 1 hour, at a temperature of 220-230°C for 5 hours. A method for the treatment of bacterial vaginosis in gynecology, including sanitation with a molded carbon sorbent modified with a glycolic acid polymer, is described.

EFFECT: technical result of the invention is the production of a molded carbon sorbent modified with glycolic acid, which has an effective bactericidal effect for the treatment of bacterial vaginosis.

4 cl, 3 dwg, 4 tbl, 9 ex