METHOD OF TREATMENT OF BACTERIAL VAGINOSIS Russian patent published in 2023 - IPC A61K35/741 A61K31/417 A61K35/74 A61P15/02 A61P31/04 

Abstract RU 2805786 C2

FIELD: medicine; gynecology; dermatovenerology.

SUBSTANCE: invention can be used in antenatal clinics and clinics for the treatment of bacterial vaginosis. An antimicrobial drug to treat bacterial vaginosis and a probiotic are administered together. A pre-selected probiotic for vaginal use capable of maximally increasing the level of adenosine triphosphoric acid production by microorganisms associated with bacterial vaginosis — Gardnerella vaginalis, Mobiluncus spp. and Prevotella bivia is used. Before starting treatment for bacterial vaginosis, a sample of cervicovaginal contents is obtained from the patient; cultures of microorganisms associated with bacterial vaginosis are isolated from the obtained sample using bacteriological methods; pre-obtained metabolites of 4 probiotic strains are sequentially added to the following isolated cultures: 3 strains of Lactobacillus acidophilus isolated from the Laktonorm, Ecofemin, Gynoflor, and one strain of Lactobacillus casei subsp. rhamnosus Lcr35 isolated from Laktozhinal. Then the change in the level of adenosine triphosphoric acid production is assessed.

EFFECT: invention provides highly effective treatment of bacterial vaginosis.

1 cl, 2 tbl, 3 ex

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RU 2 805 786 C2

Authors

Sgibnev Andrei Viktorovich

Kremleva Elena Aleksandrovna

Cherkasova Iuliia Igorevna

Krainikova Daria Aleksandrovna

Rogovaia Iuliia Leonidovna

Dates

2023-10-24Published

2022-08-02Filed