FIELD: medicine; gynecology; dermatovenerology.
SUBSTANCE: invention can be used in antenatal clinics and clinics for the treatment of bacterial vaginosis. An antimicrobial drug to treat bacterial vaginosis and a probiotic are administered together. A pre-selected probiotic for vaginal use capable of maximally increasing the level of adenosine triphosphoric acid production by microorganisms associated with bacterial vaginosis — Gardnerella vaginalis, Mobiluncus spp. and Prevotella bivia is used. Before starting treatment for bacterial vaginosis, a sample of cervicovaginal contents is obtained from the patient; cultures of microorganisms associated with bacterial vaginosis are isolated from the obtained sample using bacteriological methods; pre-obtained metabolites of 4 probiotic strains are sequentially added to the following isolated cultures: 3 strains of Lactobacillus acidophilus isolated from the Laktonorm, Ecofemin, Gynoflor, and one strain of Lactobacillus casei subsp. rhamnosus Lcr35 isolated from Laktozhinal. Then the change in the level of adenosine triphosphoric acid production is assessed.
EFFECT: invention provides highly effective treatment of bacterial vaginosis.
1 cl, 2 tbl, 3 ex
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Authors
Dates
2023-10-24—Published
2022-08-02—Filed